Zeno Clash is a fighting game mixed with first-person shooter elements. The gameplay has a strong focus on melee fighting that blends with ranged combat using unconventional weapons. The game is set in the world of Zenozoik, where the player visits extreme and exotic places. In addition to the single-player story, Challenge Mode allows the player to defeat enemies while climbing a tower. The results are ranked through Steam Friends every time the player beats a tower floor's final boss.
